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Size: 615 Kb.. epub_ ebook pdf_Ibuprofen overdose in a suicidal subject. A 22-year-old man was found dead by his girlfriend and her roommate. The only finding on the scene was ibuprofen. He had taken in excess of 200 pills in the 3 days before death. The initial autopsy report of the police suggested a homicide, but as the body was not sent for toxicological analysis, a sudden death verdict was given. A second autopsy performed at our institution revealed no contraindications to the toxicological analysis of the body fluids. In this case, after the oral fluid administration, the blood/plasma concentrations of ibuprofen were comparable to those in cases of accidental or intentional overdose reported in the literature. The toxicological analysis of the bile and gastric contents was significant for the presence of ibuprofen and paracetamol, but not in toxic concentrations.By Nate Raymond, Senior Staff Writer | April 19, 2010 Ibuprofen, the most popular nonprescription pain reliever in the U.S., is associated with an increased risk of developing dementia, depression and Alzheimer’s disease, according to a new study published in the Archives of Internal Medicine. The study, published this month, was one of the first to examine the long-term health risks of ibuprofen in seniors, who are particularly vulnerable to adverse reactions from the medication. Previous research has linked ibuprofen to liver damage and heart failure. In the study, published in the Archives of Internal Medicine, the researchers evaluated the link between ibuprofen use and dementia, depression and Alzheimer’s disease. The study compared 731 adults who took ibuprofen for 12 weeks with 732 adults who took a placebo. “This study, combined with others, makes it clear that the risks of taking over-the-counter medications are significant,” said lead author Chris McCarty, an assistant professor in the department of medicine at Harvard Medical School. “People need to be aware that taking these drugs is not a ‘get out of jail free’ card for health problems that are serious enough to warrant




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